ROTA
(Retinal Nerve Fiber Layer Optical Texture Analysis)
視網膜神經纖維層光學紋理分析
What is ROTA?
甚麼是ROTA？
ROTA (Retinal nerve fiber layer Optical Texture Analysis) is a technique used in ophthalmology to assess the health of the retinal nerve fiber layer (RNFL), which is a layer of nerve fibers that carries visual signals from the eye to the brain. ROTA involves analyzing the texture patterns of the RNFL using optical coherence tomography (OCT) imaging.
視網膜神經纖維層光學紋理分析（ROTA）是眼科學中用於評估視網膜神經纖維層（RNFL）健康狀況的一種技術，它使用光學相干斷層掃描（OCT）成像分析RNFL的紋理模式。
What is the difference between ROTA and the traditional technique?
ROTA與傳統技術有甚麼分別？
The traditional optical coherence tomography (OCT) is a non-invasive imaging technique that uses light waves to create high-resolution, cross-sectional images of the retina. ROTA uses advanced computer algorithms to analyze the texture patterns in these images, which can reveal subtle changes in the RNFL that may be indicative of various eye diseases, such as glaucoma, optic neuritis, and multiple sclerosis.
傳統的光學相干斷層掃描（OCT）是一種無創成像技術，利用光波創建視網膜高分辨率的橫截面圖像。 ROTA使用先進的計算機算法分析這些圖像中的紋理模式，這可以揭示RNFL的微小變化，這些變化可能是各種眼部疾病的跡象，如青光眼、視神經炎和多發性硬化症。
Why is ROTA significant?
ROTA為何重要？
ROTA provides clinicians with quantitative and objective measures of RNFL texture, which can help them to detect early signs of disease and monitor disease progression over time. It is an effective tool for improving the accuracy and reliability of diagnosis and treatment monitoring in ophthalmology.
ROTA為臨床醫生提供RNFL紋理的定量和客觀測量，這可以幫助他們檢測疾病的早期跡象，並隨時間監測疾病進展。它是眼科診斷和治療監測準確性和可靠性提高的有效的工具。
Publications
*The research has been published in Nature Biomedical Engineering. [1]
是次研究已在國際科學期刊《Nature Biomedical Engineering》發表。[1]
*The research has been selected for the cover of Ophthalmology Glaucoma. [3]
是次研究已被選為2023年7/8月《Ophthalmology Glaucoma》期刊的封面。[3]
[3] Ophthalmology Glaucoma. (2023). Retinal Nerve Fiber Layer Defects in Glaucoma [Cover image]. Ophthalmology Glaucoma, 6(4), 323. https://doi.org/10.1016/j.ogla.2023.06.001
Patents 專利
Leung CKS, Lam AKN. Optical Texture Analysis of the Inner Retina (US20190110681).
Principal Investigator
首席研究員
Co-investigator
共同研究員
Mr. Philip Yawen Guo
郭亞文先生
Co-investigator
共同研究員
