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Research Themes


Basic Science Research Themes
Neuroprotection in the mammalian retina
contralateral
ipsilateral
Neuronal death in retina of normal mice after transient ischemia
 
Gene therapy for diabetic, ischaemia and hereditary retinal diseases
 
Cell transplantation for the treatment of degenerative diseases
Clinical Research Themes
Diabetic retinopathy is the 
commonest cause of blindness in patients below 65 years of age
Age-related macular degeneration 
severely affects the quality of 
life in elderly patients
Retinal detachment is common
amongst short-sighted people 
and causes blindness if not treated with early and successful surgery
New Intraocular tamponade agents
are developed for the treatment
of difficult retinal detachments 
complicated by proliferative 
vitreoretinopathy
  1. In glaucoma, the retinal ganglion cells (RGCs) degenerate rapidly. Transcorneal electrical stimulation (TES) is under study to assess its neuroprotective effect in glaucoma.

  2. In normal tension glaucoma, ocular perfusion plays an important role in the disease development and progression. Subjects on hemodialysis are studied to evaluate the effect of hemodynamic change on the optic nerve.

  3. Corneal biomechanical property research projects are conducted to study its relationship with glaucoma and intraocular pressure measurement. Corneal elasticity measurement, intraocular pressure measurement using transducer and corneal collagen cross-linking are used.